Publications from the P. LiWang Group

University of California, Merced

RECENT PEER-REVIEWED PUBLICATIONS

• "Structural insights into the interaction between a potent anti-inflammatory protien, vCCI and the human CC chemokine, Eotaxin-1" Nai-wei Kuo, Yong-Guang Gao, Megan s. Schill, Nancy Isern, Cynthia M. Dupurerur, and Patricia J. LiWang J. Biol Chem 289, 6592-6603 (2014).

• "A comparison of 5P12-vMIP-II and vMIP-II as HIV-1 entry inhibitors" Jie Xue, Nai-wei Kuo, Megan Schill, and Patricia J. LiWang Biochemistry and Physiology S2.doi:10.1371/journal.pone.0064132 (2013).

• “The griffithsin dimer is required for high potency inhibition of HIV-1: Evidence for manipulation of the structure of gp120 as part of the griffithsin dimer mechanism” Jie Xue, Bart Hoorelbeke, Ioannis Kagiampakis, Borries Demeler, Jan Balzarini, and Patricia J. LiWang Antimicrobial Agents and Chemotherapy 57:8, 3976–3989 (2013).

• “HIV-1 envelope trimer has similar binding characteristics for carbohydrate-binding agents as monomeric gp120” Bart Hoorelbeke, Thijs van Montfort, Jie Xue, Patricia J. LiWang, Haruo Tanaka, Yasuhiro Igarashi, Els J.M. Vandamme, Rogier Sanders, and Jan Balzarini FEBS Letters 587, 860-866 (2013).

• “Role of the carbohydrate-binding sites of griffithsin in the prevention of DC-SIGN-mediated capture and transmission of HIV-1” Bart Hoorelbeke, Jie Xue, Patricia J. LiWang , and Jan Balzarini PLoS ONE 8(5): e64132. doi:10.1371/journal.pone.0064132 (2013).

• "A comparison of 5P12-vMIP-II and vMIP-II as HIV-1 entry inhibitors" Jie Xue, Nai-Wei Kuo, Megan Schill, and Patricia J. LiWang Biochemistry and Physiology S2. doi:10.4172/2168-9652.S2-005 (2013).

• "The role of individual carbohydrate-binding sites in the function of the potent anti-HIV lectin Griffithsin" Jie Xue, Yongguang Gao, Bart Hoorelbeke, Ioannis Kagiampakis, Bo Zhao, Borries Demeler, Jan Balzarini, and Patricia J. LiWang. Molecular Pharmaceutics 4, 2613-2625 (2012)

• "Highly potent chimeric inhibitors targeting two steps of HIV cell entry"Bo Zhao, Marie K. Mankowski, Beth A. Snyder, Roger G. Ptak and Patricia J. LiWangJournal of Biological Chemistry 286, 28370-28381 (2011).

• “A Potent Strategy to Inhibit HIV by binding both gp120 and gp41”
Ioannis Kagiampakis, Arbi Gharibi, Marie K. Mankowski, Beth A. Snyder, Roger G. Ptak, Kristabelle Alatas, and Patricia J. LiWangAntimicrobial Agents and Chemotherapy 55, 254-265 (2011).

• “Characterization of the interactions of vMIP-II, and a dimeric variant of vMIP- II, with glycosaminoglycans”
Bo Zhao and Patricia J. LiWang Biochemistry 49, 7012-7022 (2010).

• “Structural and Functional Studies of the Potent Anti-HIV Chemokine Variant P2-RANTES” Hongjun Jin, Ioannis Kagiampakis, Pingwei Li and Patricia J. LiWang Proteins:Structure, Function and Bioinformatics 78, 295-308 (2010).

• "University of California Research Seminar Network: A Prospectus" James R. Carey, John Laursen, Steven Glaser, Stephen Raphael, Gregory Miller, John Crawford, Timothy Lane, Patricia LiWang , Kimberly Hammond, Theodore Groves, Jean- Francois Pittet, David Stuart, Phokion Kolaitis, Laura Serwer, Mengfei Chen, Kenneth Feer PLoS Biology 8 issue 1 (2010).

•  "Conservation of unfavorable sequence motifs that contribute to chemokine quaternary state"
Ioannis Kagiampakis, Hongjun Jin, Sinae Kim, Marina Vannucci, Patricia LiWang, and Jerry Tsai,
Biochemistry 47, 10637-10648 (2008).

• “The human CC chemokine MIP-1b dimer is not competent to bind to the CCR5 receptor” Hongjun Jin, Xiaohong Shen, Brandi Renee Baggett, Xiangming Kong and Patricia J. LiWang Journal Biol. Chem 282, 27976-27983 (2007).

• “Detecting protein dissimilarities in multiple alignments using Bayesian variable selection” Sinae Kim, Jerry Tsai, Ioannis Kagiampakis, Patricia J. LiWang, and Marina Vanucci Bioinformatics 23, 245-246 (2007).

• “Solution structure of the complex between poxvirus-encoded CC chemokine inhibitor vCCI and human MIP-1b” Li Zhang, Michele DeRider, Melissa A. McCornack, Chris Jao, Traci Ness, Richard Moyer, and Patricia J. LiWang Proc. Natl. Acad. Sci. USA (2006).

• “Resonance assignments of the 34 kD rabbitpox vCCI:human MIP-1b complex” Li Zhang and Patricia J. LiWang J. Biomol. NMR (2006).

• “Resonance assignments and secondary structure of vCCI, a 26 kDa soluble secreted chemokine inhibitor from rabbitpox virus” Michele L. DeRider, Li Zhang, and Patricia J. LiWang J. Biomol. NMR (March 2006).

• “Investigation of CC and CXC chemokine quaternary state mutants” Hongjun Jin, Garret L. Hayes, Nithyanada S. Darbha, Erik Meyer and Patricia J. LiWang Biochem. Biophys. Res. Comm. 338, 987-999 (2005).

• “CC and CX3C chemokines differentially interact with the N-terminus of the human cytomegalovirus-encoded US28 receptor” Paola Casarosa, Maria Wahldhoer, Patricia J. LiWang, Henry Vischer, Thomas Kledal, Henk Timmerman, Thue W. Schwartz, Martine J. Smit, and Rob Leurs J. Biol. Chem. 280, 3275 - 3285 (2005).

• “Glycosaminoglycan Disaccharide Alters the Dimer Dissociation Constant of the Chemokine MIP-1b" Melissa A. McCornack, Danielle M. Boren, and Patricia J. LiWang “Glycosaminoglycan Disaccharide Alters the Dimer Dissociation Constant of the Chemokine MIP-1b" Biochemistry 43, 10090-10101 (2004).

• Melissa A. McCornack, Craig K. Cassidy, and Patricia J. LiWang "The binding surface and affinity of monomeric and dimeric chemokine MIP-1b for various glycosaminoglycan disaccharides" J. Biol. Chem. 278, 1946-1956 (2003).

• Amanda E. I. Proudfoot, Zoe Johnson, Tracy Handel, Elaine Lau, Patricia LiWang, Ian Clark-Lewis, Frédéric Borlat, Timothy N.C. Wells and Marie Kosco-Vilbois "Glycosaminoglycan binding and oligomerization is essential for the in vivo activity of certain chemokines" Proc Natl. Acad. Sci. USA 100,1885-1890 (2003).

• Yufeng Zhang, Huangshang Lu, Patricia LiWang, Uluhan Sill, and Nancy S. Templeton “Optimization of Gene Expression in Nonactivated Circulating Lymphocytes” Molecular Therapy 8, 629-636 (2003).

• Antoine Bondue, Shu-chuan Jao, Cédric Blanpain, Marc Parmentier, and Patricia J. LiWang* "Characterization of the role of the N-Loop of MIP-1b in CCR5 binding" Biochemistry 41, 13548-13555 (2002).

• Seho Kim, Shu-chuan Jao, Jennifer S. Laurence, and Patricia J. LiWang "Structural comparison of monomeric variants of the chemokine MIP-1b having differing ability to bind the receptor CCR5" Biochemistry 40, 10782-10791 (2001).

• Jennifer S. Laurence, Cédric Blanpain, Anne De Leener, Marc Parmentier, and Patricia J. LiWang* "The Importance of Basic Residues and Quaternary Structure in the Function of MIP-1b: CCR5 Binding and Cell Surface Sugar Interactions" Biochemistry 40, 4990-4999 (2001).

• Jennifer S. Laurence, Blanpain, C., Burgner, J.W., Parmentier, M., and Patricia J. LiWang* "CC chemokine MIP-1b can function as a monomer and depends on Phe13 for receptor binding" Biochemistry 39, 3401-3409 (2000).

• Andy C. LiWang, Wang, Z.-X., Sun, Y., Peiper, S.C., and Patricia J. LiWang* "The solution structure of the anti-HIV chemokine vMIP-II" Protein Science 8, 2270-2279 (1999).

• Andy C. LiWang, Jian Jing Cao, Hong Zheng, Zhaohai Lu, Stephen C. Peiper, and Patricia J. LiWang* "A Dynamics Study On the Anti-HIV Chemokine vMIP-II Reveals a Fully Monomeric Protein" Biochemistry 38, 442-453 (1999).

• Jennifer S. Laurence., LiWang, A.C., and Patricia J. LiWang* "The Effect of N-terminal Truncation and Solution Conditions on Chemokine Dimer Stability: NMR Structural Analysis of MIP-1b mutants" Biochemistry 37, 9346-9354 (1998).