The Oviedo Lab studies planarians to understand the mechanisms of stem cell regulation.

Publications

Articles

TOR Signaling Regulates Planarian Stem Cells and Controls Localized and Organismal Growth.

Harshani T. Peiris, Frank Weckerle, Elyse Ozamoto, Daniel Ramirez, Devon Davidian, Marcos García-Ojeda and Néstor J. Oviedo (2012).

PDF Document Journal of Cell Science. Mar 22. [Epub ahead of print]

Gap junction proteins: Master regulators of the planarian stem cell response to tissue maintenance and injury.

Harshani T. Peiris and Néstor J. Oviedo (2012).

PDF Document Biochim Biophys Acta. Mar 16. [Epub ahead of print].

Long-range neural and gap junction protein-mediated cues control polarity during planarian regeneration.

Néstor J. Oviedo, Junji Morokuma, Peter Walentek, Ido Kema, Man Bock Gu, Joo Myung Ahn, Hwang Jung Shan, Takashi Gojobori and Michael Levin (2010).

PDF Document Developmental Biology. 339: 188-199 Publication Cover

Regeneration: the origin of cancer or a possible cure?

Néstor J. Oviedo*, Wendy Beane (2009).

PDF Document Seminars in Cell and Developmental Biology. 20:557-564

Planarian PTEN homologs regulate stem cells and regeneration through TOR signaling.

Néstor J. Oviedo*, Bret Pearson, Michael Levin and Alejandro Sánchez Alvarado* (2008).

PDF Document Disease Models and Mechanisms. 1: 131-143

smedinx-11 is a planarian stem cell gap junction gene required for regeneration and homeostasis.

Néstor J. Oviedo, and Michael Levin (2007).

PDF Document Development. 134:3121-3131

Gap junctions provide new links in left-right patterning.

Néstor J. Oviedo and Michael Levin (2007)

PDF Document Cell. 18;129(4):645-647

SMEDWI-2 is a PIWI-like protein that regulates planarian stem cells.

Peter W. Reddien, Néstor J. Oviedo, Joya R. Jennings, James C. Jenkin and Alejandro Sánchez Alvarado (2005)

PDF Document Science. 310:1327-1330

Allometric scalling and proportion regulation in the freshwater planarian Schmidtea mediterranea.

Néstor J. Oviedo, Phillip A. Newmark and Alejandro Sánchez Alvarado (2003)

PDF Document Developmental Dynamics. 226:326-333 Publication Cover

* Corresponding author(s).

Book Chapters

Planaria: a versatile and powerful model system for molecular studies of regeneration, adult stem cell regulation, aging and behavior.

Néstor J. Oviedo, Cindy Nicolas, Dany S. Adams and Michael Levin (2008)

HTML Page Emerging Model Organisms, A Laboratory Manual
HTML Page Cold Spring Harbor Protocols. doi:10.1101/pdb.emo101
HTML Page

Establishing and Maintaining a colony of planarians

Cold Spring Harb. Protoc.; 2008; doi:10.1101/pdb.prot5053
HTML Page

Gene knockdown in planarians using RNA interference

Cold Spring Harb. Protoc.; 2008; doi:10.1101/pdb.prot5054
HTML Page

Live imaging of planarian membrane potential using DiBAC4(3)

Cold Spring Harb. Protoc.; 2008; doi:10.1101/pdb.prot5055

The planarian regeneration model as a context for the study of drug effects and mechanisms.

Néstor J. Oviedo and Michael Levin (2008)

HTML Page Planaria: A model for drug action and abuse

R. Raffa, ed. Intelligence Unit Series, Landes Bioscience. Austin.

Other Publications

The plasma membrane Ca+2-ATPase from red blood cells is not modified in preeclampsia.

Néstor J. Oviedo, Gustavo Benaim, Vincenza Cervino, Teresa Proverbio, Fulgencio Proverbio and Reinaldo Marín (2006)

PDF Document Biochimica et Biophysica Acta, 1762: 381-385

Calcium-ATPase activity of red blood cell ghost from preeclamptic women, antepartum and postpartum.

Thairis T. López, Flor Limongi, Teresa Proverbio, Néstor J. Oviedo, Fulgencio Proverbio and Reinaldo MarÍn (2003)

PDF Document Hypertension in Pregnancy, 22: (3) 247-256
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