Welcome to the Nobile Lab
Research in the Nobile lab is directed towards understanding the molecular and mechanistic bases of microbial communities, such as biofilms. We are interested in investigating how transcriptional networks underlie the regulation of gene expression during the development of a microbial community.
Much of this work is carried out in the species Candida albicans, the most prevalent fungal pathogen and commensal of humans. The lab is also beginning to study interspecies interactions between different fungal and bacterial species.
Questions we are currently pursuing include: How are microbial communities regulated? How are microbial communities built? How are their unique and specialized properties maintained? How have microbial communities evolved?